Publications
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2024
“Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance”
Vasudevan HN, Payne E, Delley CL, John Liu S, Mirchia K, Sale MJ, Lastella S, Nunez MS, Lucas CG, Eaton CD, Casey-Clyde T, Magill ST, Chen WC, Braunstein SE, Perry A, Jacques L, Reddy AT, Pekmezci M, Abate AR, McCormick F, Raleigh DR.
Nat Commun., 15(1):477. doi: 10.1038/s41467-024-44755-9. PMID: 38216572; PMCID: PMC10786885.
2023
“Droplet-based microfluidics”
Moragues T, Arguijo D, Beneyton T, Modavi C, Simutis K, Abate AR, Baret JC, deMello AJ, Densmore D, Griffiths AD.
Nat Rev Methods Primers., 3, 32. DOI: 10.1038/s43586-023-00212-3
“Viral load quantitation at the point-of-care with shaken digital droplet RT-LAMP”
Weisgerber DW, Langer K, Servellita V, Xu P, Chiu CY, Abate AR.
Lab Chip., 23(15):3479-3486. DOI: 10.1039/d3lc00096f.
“Flow cytometric printing of double emulsions into open droplet arrays”
Zhang P, Xu L, Chen H, Abate AR.
Lab Chip., 23(10):2371-2377. DOI: 10.1039/d3lc00151b.
“Droplet-based forward genetic screening of astrocyte–microglia cross-talk”
Wheeler MA, Clark IC, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ.
Science., 379(6636):1023-1030. DOI: 10.1126/science.abq4822.
“Microfluidics-free single-cell genomics with templated emulsification”
Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR.
Nat Biotechnol., 41(11):1557-1566. DOI: 10.1038/s41587-023-01685-z.
“HIV silencing and cell survival signatures in infected T cell reservoirs”
Clark IC, Mudvari P, Thaploo S, Smith S, Abu-Laban M, Hamouda M, Theberge M, Shah S, Ko SH, Pérez L, Bunis DG, Lee JS, Kilam D, Zakaria S, Choi S, Darko S, Henry AR, Wheeler MA, Hoh R, Butrus S, Deeks SG, Quintana FJ, Douek DC, Abate AR, Boritz EA
Nature., 614(7947):318-325. DOI: 10.1038/s41586-022-05556-6
“Identification of astrocyte regulators by nucleic acid cytometry”
Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, Zandee SEJ, Prat A, Douek DC, Boritz EA, Quintana FJ, Abate AR
Nature., 614(7947):326-333. DOI: 10.1038/s41586-022-05613-0
2022
“Rapid parallel generation of a fluorescently barcoded drop library from a microtiter plate using the plate-interfacing parallel encapsulation (PIPE) chip”
Zath GK, Sperling RA, Hoffman CW, Bikos DA, Abbasi R, Abate AR, Weitz DA, Chang CB
Lab Chip., 22(23):4735-4745. DOI: 10.1039/d2lc00909a
“Metagenomic data using StrainFacts”
Smith BJ, Li X, Shi ZJ, Abate A, Pollard KS
Bioinform., 2:867386. DOI: 10.3389/fbinf.2022.867386
“Polyhedral Particles with Controlled Concavity by Indentation Templating”
Weisgerber DW, Hatori M, Li X, Abate AR
Anal Chem., 94(21):7475-7482. DOI: 10.1021/acs.analchem.1c04884
“Controlled fabrication of functional liver spheroids with microfluidic flow cytometric printing”
Zhang P, Li X, Chen JY, Abate AR
Biofabrication., 14(4). DOI: 10.1088/1758-5090/ac8622
“Droplet-microfluidics-assisted sequencing of HIV proviruses and their integration sites in cells from people on antiretroviral therapy”
Sun C, Liu L, Pérez L, Li X, Liu Y, Xu P, Boritz EA, Mullins JI, Abate AR
Nat Biomed Eng., 6(8):1004-1012. DOI: 10.1038/s41551-022-00864-8
“Robotic automation of droplet microfluidics”
Tran TM, Kim SC, Modavi C, Abate AR
Biomicrofluidics., 16(1):014102. DOI: 10.1063/5.0064265
“Dual-layered hydrogels allow complete genome recovery with nucleic acid cytometry”
Hatori MN, Modavi C, Xu P, Weisgerber D, Abate AR
Biotechnol J., 17(4):e2100483. DOI: 10.1002/biot.202100483
“Characterizing cell interactions at scale with made-to-order droplet ensembles (MODEs)”
Madrigal JL, Schoepp NG, Xu L, Powell CS, Delley CL, Siltanen CA, Danao J, Srinivasan M, Cole RH, Abate AR
PNAS., 119(5):e2110867119. DOI: 10.1073/pnas.2110867119
“Microbowls with Controlled Concavity for Accurate Microscale Mass Spectrometry”
Xu L, Li X, Li W, Chang KC, Yang H, Tao N, Zhang P, Payne EM, Modavi C, Humphries J, Lu CW, Abate AR
Adv Mater., 34(12):e2108194. DOI: 10.1002/adma.202108194
“The chromatin repressors EZH2 and Suv4-20h coregulate cell fate specification during hippocampal development”
Chang KC, Rhodes CT, Zhang JQ, Moseley MC, Cardona SM, Huang SA, Rawls A, Lemmon VP, Berger MS, Abate AR, Lin CA
FEBS Lett., 596(3):294-308. DOI: 10.1002/1873-3468.14254
2021
“Mapping enzyme catalysis with metabolic biosensing”
Xu L, Chang KC, Payne EM, Modavi C, Liu L, Palmer CM, Tao N, Alper HS, Kennedy RT, Cornett DS, Abate AR
Nature Communications, DOI: 10.1038/s41467-021-27185-9
“Single-Cell Protein Profiling by Microdroplet Barcoding and Next-Generation Sequencing”
Kim SC, Haliburton JR, Gartner ZJ, Abate AR.
Methods in Molecular Biology, DOI: 10.1007/978-1-0716-1771-7_7
“Change can be SCARI”
Modavi C, Abate AR.
Nat. Chem. Biol., DOI: 10.1038/s41589-021-00859-7
“Accurate Bulk Quantitation of Droplet Digital Polymerase Chain Reaction”
Sun C, Leqian L, Vasudevan HN, Chang KC, Abate AR.
Anal Chem., DOI: 10.1021/acs.analchem.1c00877
“Modular barcode beads for microfluidic single cell genomics”
Delley CL, Abate AR.
Scientific Reports, DOI: 10.1038/s41598-021-90255-x
“Sequencing Ultrarare Targets with Compound Nucleic Acid Cytometry”
Sun C, Chang KC, Abate AR.
Anal Chem., DOI: 10.1021/acs.analchem.0c04749
“Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients”
Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL,Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N.
J Exp Med., DOI: 10.1084/jem.20201750
“Barcoded viral tracing of single-cell interactions in central nervous system inflammation”
Clark I.C., Gutiérrez-Vázquez C., Wheeler M.A., Li Z., Rothhammer V., Linnerbauer M., Sanmarco L.M., Guo L., Blain M., Zandee S.E.J., Chao C.C., Batterman K.V., Schwabenland M., Lotfy P., Tejeda-Velarde A., Hewson P., Manganeli Polonio C., Shultis M.W., Salem Y., Tjon E.C., Fonseca-Castro P.H., Borucki D.M., Alves de Lima K., Plasencia A., Abate A.R., Rosene D.L., Hodgetts K.J., Prinz M., Antel J.P., Prat A., Quintana F.J.
Science, DOI: 10.1126/science.abf1230
“Protein design-scapes generated by microfluidic DNA assembly elucidate domain coupling in the bacterial histidine kinase CpxA”
Clark, I.C., Mensa, B., Ochs, C.J., Schmidt, N.W., Mravic, M., Quintana, F.J., DeGrado, W.F. and Abate, A.R.
PNAS, DOI: 10.1073/pnas.201771911
"Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia"
Demaree, B.*, Delley, C.L.*, Vasudevan, H.N., Peretz, C.A., Ruff, D., Smith, C.C. and Abate, A.R.
Nature Communications, DOI: 10.1038/s41467-021-21810-3
"Particle Templated Emulsification enables Microfluidic-Free Droplet Assays"
Weisgerber, D.W., Hatori, M.N. and Abate, A.R.
J. Vis. Exp., DOI: 10.3791/62248
“Precision ejection of microfluidic droplets into air with a superhydrophobic outlet”
Zhang, P., Chang, K.C. and Abate, A.R.
Lab on a Chip, DOI: 10.1039/d0lc01327g
“High diversity droplet microfluidic libraries generated with a commercial liquid spotter”
Zhang, J.Q., Siltanen, C.A., Dolatmoradi, A., Sun, C., Chang, K.C., Cole, R.H., Gartner, Z.J. and Abate, A.R.
Scientific Reports, DOI: 10.1038/s41598-021-83865-y
“Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification”
Vasudevan, H.N., Xu, P., Servellita, V., Miller, S., Liu, L., Gopez, A., Chiu, C.Y. and Abate, A.R.
Scientific Reports, DOI: 10.1038/s41598-020-80715-1
2020
“High‐Definition Single‐Cell Printing: Cell‐by‐Cell Fabrication of Biological Structures”
Zhang, P. and Abate, A.R.
Advanced Materials, DOI: 10.1002/adma.202005346
"Single-cell mutation analysis of clonal evolution in myeloid malignancies"
Miles, L.A., Bowman, R.L., Merlinsky, T.R., Csete, I.S., Ooi, A.T., Durruthy-Durruthy, R., Bowman, M., Famulare, C., Patel, M.A., Mendez, P., Ainali, C.,
Demaree, B., Delley, C.L., Abate, A.R., Manivannan, M., Sahu, S., Goldberg, A.D., Bolton, K.L., Zehir, A., Rampal, R., Carroll, M.P., Meyer, S.E., Viny,
A.D. and R.L. Levine.
Nature, DOI: 10.1038/s41586-020-2864-x
"Targeted Single-Cell RNA and DNA Sequencing With Fluorescence-Activated Droplet Merger"
Clark, I.C., Delley, C.L., Sun, C., Thakur, R., Stott, S.L., Thaploo, S., Li, Z., Quintana, F.J. and A.R. Abate
Analytical Chemistry, DOI: 10.1021/acs.analchem.0c03059
“Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma”
Magill, S.T., Vasudevan, H.N., Seo, K., Villanueva-Meyer, J.E., Choudhury, A., Liu, S.J., Pekmezci, M., Findakly. S., Hilz, S., Lastella, S., Demaree, B.,
Braunstein, S.E., Bush, N.A.O., Aghi, M.K., Theodosopoulos, P.V., Sneed, P.K., Abate, A.R., Berger, M.S., McDermott, M.W., Lim, D.A., Ullian, E.M.,
Costello, J.F., Raleigh, D.R.
Nature Communications, DOI: 10.1038/s41467-020-18582-7
“Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions”
Finbloom, J.A., Demaree, B., Abate, A.R. and Desai, T.A.
Advanced Functional Materials, DOI: 10.1002/adfm.202005938
“Microfluidic particle zipper enables controlled loading of droplets with distinct particle types”
Delley, C.L. and Abate, A.R.
Lab on a Chip, DOI: 10.1039/D0LC00339E
“High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing”
Zhang, J.Q., Chang, K.C., Liu, L., Gartner, Z.J. and Abate, A.R.
J. Vis. Exp., DOI: 10.3791/61014
“Linked optical and gene expression profiling of single cells at high-throughput”
Zhang, J.Q., Siltanen, C.A., Liu, L., Chang, K.C., Gartner, Z.J. and Abate, A.R.
Genome Biology, DOI: 10.1186/s13059-020-01958-9
“Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery”
Xu, P., Modavi, C., Demaree, B., Twigg, F., Liang, B., Sun, C., Zhang, W. and Abate, A.R
Nucleic Acids Research, DOI: 10.1093/nar/gkaa131
“Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma”
Liu, S.J., Magill, S.T., Vasudevan, H.N., Hilz, S., Villanueva-Meyer, J.E., Lastella, S., Daggubati, V., Spatz, J., Choudhury, A., Orr, B.A, Demaree, B.,
Seo, K., Ferris, S.P., Abate, A.R., Oberheim Bush, N.A., Bollen, A.W., McDermott, M.W., Costello, J.F., Raleigh, D.R.
Cell Reports, DOI: 10.1016/j.celrep.2020.01.018
“Discovery of Stable and Selective Antibody Mimetics from Combinatorial Libraries of Polyvalent, Loop-Functionalized Peptoid Nanosheets”
Kim, J. H., Kim, S. C., Kline, M. A., Grzincic, E. M., Tresca, B. W., Cardiel, J.,..., Abate, A.R., and Jian, T.
ACS Nano, DOI: 10.1021/acsnano.9b07498
2019
“Uniform, Large-Area, Highly Ordered Peptoid Monolayer and Bilayer Films for Sensing Applications”
Murray DJ, Kim JH, Grzincic EM, Kim SC, Abate AR, Zuckermann RN
Langmuir., 35(42):13671-13680. DOI: 10.1021/acs.langmuir.9b02557
“Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport”
Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA
Sci Rep., 9(1):9936. DOI: 10.1038/s41598-019-46408-0
“High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq”
Liu L, Dalal CK, Heineike BM, Abate AR
Lab Chip., 19(10):1838-1849. DOI: 10.1039/c9lc00084d
“Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage”
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M
Nat Immunol., 20(2):163-172. DOI: 10.1038/s41590-018-0276-y
2018
“Direct quantification of EGFR variant allele frequency in cell-free DNA using a microfluidic-free digital droplet PCR assay”
B. Demaree, D. Weisgerber, A. Dolatmoradi, M. Hatori, and A.R. Abate
Methods in Cell Biology, DOI: 10.1016/bs.mcb.2018.10.002
“Microfluidic bead encapsulation above 20 kHz with triggered drop formation”
I.C. Clark and A.R. Abate
Lab on a Chip, DOI: 10.1039/C8LC00514A
"Particle-Templated Emulsification for Microfluidics-Free Digital Biology"
M.N. Hatori, S.C. Kim, and A.R. Abate
Analytical Chemistry, DOI: 10.1021/acs.analchem.8b01759
"An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing"
B. Demaree, D. Weisgerber, F. Lan, and A.R. Abate
J. Vis. Exp., DOI: 10.3791/57598
"An Oil-Free Picodrop Bioassay Platform for Synthetic Biology"
C.A. Siltanen, R.H. Cole, S. Poust, L. Chao, J. Tyerman, B. Kaufmann-Malaga, J. Ubersax, Z.J. Gartner, and A.R. Abate
Scientific Reports, DOI :10.1038/s41598-018-25577-4
"A comparative analysis of single cell and droplet-based FACS for improving production phenotypes: Riboflavin overproduction in Yarrowia lipolytica"
J.M. Wagner, L. Liu, S.F. Yuan, M.V. Venkataraman, A.R. Abate, and H.S. Alper
Metabolic Engineering, DOI: 10.1016/j.ymben.2018.04.015
"Combined aptamer and transcriptome sequencing of single cells"
C. Delley, L. Liu, M. Sarhan, and A.R. Abate
Scientific Reports, DOI: 10.1038/s41598-018-21153-y
"Concentric electrodes improve microfluidic droplet sorting"
I.C. Clark, R. Thakur, and A.R. Abate
Lab on a Chip, DOI: 10.1039/C7LC012J
2017
"Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis"
S.C. Kim, I.C. Clark, P. Shahi, and A.R. Abate
Analytical Chemistry, DOI: 10.1021/acs.analchem.7b04050
"Bulk double emulsification for flow cytometric analysis of microfluidic droplets"
D.J. Sukovich, S.C. Kim, N. Ahmed and A.R. Abate
Analyst, DOI:10.1039/c7an01695f
"RNA-aptamers-in-droplets (RAPID) high throughput screening for secretory phenotypes"
J. Abatemarco , M.F. Sarhan, J. M. Wagner , J-L. Lin , L. Liu, W. Hassouneh, S-F. Yuan , H.S. Alper and A.R. Abate
Nature Communications, DOI: 10.1038/s41467-017-00425-7
"Cell-free extract based optimization of biomolecular circuits with droplet microfluidics"
Y. Hori, C. Kantak, R.M. Murray and A.R. Abate
Lab on a Chip, DOI: 10.1039/c7lc00552k
"Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells"
R.H. Cole, S. Tang , C. A. Siltanen , P. Shahi , J.Q. Zhang, S. Pousta , Z.J. Gartner and A.R. Abate
PNAS, DOI: 10.1073/pnas.1704020114
"Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun"
M. Karbaschi, P. Shahi, and A.R. Abate
Biomicrofluidics, DOI: 10.1063/1.4995479
"Measurement of copy number variation in single cancer cells using rapid-emulsification digital droplet MDA"
S. C. Kim, G. Premasekharan, I. C. Clark, H. B. Gemeda, P. L. Paris and A. R. Abate
Microsystems & Nanoengineering, DOI: 10.1038/micronano.2017.18
"Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding"
F. Lan, B. Demaree, N. Ahmed, and A.R. Abate
Nature Biotechnology, DOI: 10.1038/nbt.3880
"Efficient extraction of oil from droplet microfluidic emulsions"
J. R. Haliburton, S. C. Kim, I.C. Clark, R. A. Sperling, D. A. Weitz, and A. R. Abate
Biomicrofluidics, DOI: 10.1063/1.4984035
"Finding a helix in a haystack: nucleic acid cytometry with droplet microfluidics"
I. C. Clark and A. R. Abate
Lab on a Chip, DOI: 10.1039/C7LC00241F, Critical Review
"Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding"
P. Shahi, S. C. Kim, J. R. Haliburton, Z. J. Gartner & A. R. Abate
Scientific Reports, DOI: 10.1038/srep44447
"Genetic interaction mapping with microfluidic-based single cell sequencing"
J. R. Haliburton, W. Shao, A. Deutschbauer, A. Arkin, and A. R. Abate
PloS One, DOI: 10.1371/journal.pone.0171302
"PCR-activated cell sorting as a general, cultivation-free method for high-throughput identification and enrichment of virus hosts"
S. W. Lim, S. T. Lance, K. M. Stedman, Adam R. Abate
Journal of Virological Methods, DOI: 10.1016/j.jviromet.2016.12.009
2016
"Sequence specific sorting of DNA molecules with FACS using 3dPCR"
D. J. Sukovich, S. T. Lance, and A. R. Abate
Scientific Reports, DOI: 10.1038/srep39385
"Peering below the diffraction limit: robust and specific sorting of viruses with flow cytometry"
S. T. Lance, D. J. Sukovich, K. M. Stedman and A. R. Abate
Virology Journal, DOI: 10.1186/s12985-016-0655-7
"Rapid Encapsulation of Cell and Polymer Solutions with Bubble-Triggered Droplet Generation"
Z. Yan, I. C. Clark, A. R. Abate
Macromolecular Chemistry and Physics, DOI: 10.1002/macp.201600297
"Operation of Droplet-Microfluidic Devices with a Lab Centrifuge"
N. Ahmed, D. Sukovich and A. R. Abate
Micromachines 2016, 7(9), 161; DOI: 10.3390/mi7090161
"Droplet barcoding for massively parallel single-molecule deep sequencing"
F. Lan, J. R. Haliburton, A. Yuan, A. R. Abate
Nature Communications 7, Article number: 11784 (2016) doi:10.1038/ncomms11784
"Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers."
Cole, R. H., Gartner, Z. J., Abate, A. R.
J. Vis. Exp., DOI: 10.3791/54010
"Electrical lysis of cells for detergent-free droplet assays"
N. de Lange, T. M. Tran and A. R. Abate
Biomicrofluidics, DOI: 10.1063/1.4944742
2015
"Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device"
Cole RH, Tran TM, Abate AR
J Vis Exp., (106):e53516. DOI: 10.3791/53516
"Enhanced sequencing coverage with digital droplet multiple displacement amplification"
Sidore AM, Lan F, Lim SW, Abate AR
Nucleic Acids Res., 44(7):e66. DOI: 10.1093/nar/gkv1493
"Patterning microfluidic device wettability with spatially-controlled plasma oxidation"
Kim SC, Sukovich DJ, Abate AR
Lab Chip., 15(15):3163-9. DOI: 10.1039/c5lc00626k
"Compact and modular multicolour fluorescence detector for droplet microfluidics"
Cole RH, de Lange N, Gartner ZJ, Abate AR
Lab Chip., 15(13):2754-8. doi: 10.1039/c5lc00333d
"Dissecting enzyme function with microfluidic-based deep mutational scanning"
Romero PA, Tran TM, Abate AR
PNAS., 112(23):7159-64. DOI: 10.1073/pnas.1422285112
"Microfluidic droplet enrichment for targeted sequencing"
Eastburn DJ, Huang Y, Pellegrino M, Sciambi A, Ptáček LJ, Abate AR
Nucleic Acids Res., 43(13):e86. DOI: 10.1093/nar/gkv297
"PCR-Activated Cell Sorting for Cultivation-Free Enrichment and Sequencing of Rare Microbes"
Lim SW, Tran TM, Abate AR
PLoS One., 10(1):e0113549. DOI: 10.1371/journal.pone.0113549
"Rapid modulation of droplet composition with pincer microvalves"
Ochs CJ, Abate AR
Lab Chip., 15(1):52-6. DOI: 10.1039/c4lc01040j
"Accurate sorting of microfluidic droplets at 30 kHz"
Sciambi A, Abate AR
Lab Chip., 15(1):47-51. DOI: 10.1039/c4lc01194e
"Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia"
Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML
Blood., 125(3):516-24. DOI: 10.1182/blood-2014-09-601690
2014
"Identification and genetic analysis of cancer cells with PCR-activated cell sorting"
Eastburn DJ, Sciambi A, Abate AR
Nucleic Acids Res., 42(16):e128. DOI: 10.1093/nar/gku606
"Picoinjection of Microfluidic Drops Without Metal Electrodes"
O'Donovan B, Tran T, Sciambi A, Abate AR
J Vis Exp., (86):50913. DOI: 10.3791/50913
"Generating electric fields in PDMS microfluidic devices with salt water electrodes"
Sciambi A, Abate AR
Lab Chip., 14(15):2605-9. DOI: 10.1039/c4lc00078a
"Coaxial flow focusing in poly(dimethylsiloxane) microfluidic devices"
Tran TM, Cater S, Abate AR
Biomicrofluidics., 8(1):016502. DOI: 10.1063/1.4863576
2013
"DNA sequence analysis with droplet-based microfluidics"
A. R. Abate, T. Hung, R. A. Sperling, P. Mary, A. Rotem, J. J. Agresti, M. A. Weiner, and D. A. Weitz
Lab Chip 13, 4864 (2013)
"Ultrahigh-throughput sorting of microfluidic drops with flow cytometry"
S. W. Lim, A. R. Abate
Lab Chip 13, 4563 (2013)
"Adding reagent to droplets with controlled rupture of encapsulated double emulsions"
A. Sciambi, A. R. Abate
Biomicrofluidics 7, 044112 (2013)
"Ultrahigh-throughput mammalian single-cell RT-PCR in microfluidic drops"
D. J. Eastburn, A. Sciambi, A. R. Abate
Analytical Chemistry 85, 8016-8021 (2013)
"Picoinjection Enables Digital Detection of RNA with Droplet RT-PCR"
D. J. Eastburn, A. Sciambi, and A. R. Abate
PLoS ONE 8, e62961 (2013)
"Block-and-break generation of microdroplets with fixed volume"
V. Steijn, P. M. Korczyk, L. Derzsi, A. R. Abate, D. A. Weitz, and P. Garstecki
Biomicrofluidics 7, 024108 (2013)
"From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology"
T. M. Tran, F. Lan, C. S. Thompson and A. R. Abate
Journal of Physics D: Applied Physics 46, 114004 (2013)
"Adhesive-based bonding technique for PDMS microfluidic devices"
C. S. Thompson, A. R. Abate
Lab Chip 13, 632 (2013)
2012
"Flow focusing geometry generates droplets through a plug and squeeze mechanism"
P. A. Romero, A. R. Abate
Lab Chip 12, 5130 (2012)
"Drop formation in non-planar microfluidic devices"
A. Rotem, A. R. Abate, A. S. Utada, V. Van Steijn, D. A. Weitz
Lab Chip 12, 4263 (2012)
"Electrode-free picoinjection of microfluidic drops"
B. O'Donovan, D. J. Eastburn, A. R. Abate
Lab Chip 12, 4029 (2012)
"Microfluidic synthesis of advanced microparticles for encapsulation and controlled release"
W. J. Duncanson, T. Lin, A. R. Abate, S. Seiffert, R.K. Shaw, D. A. Weitz
Lab Chip 12, 2135 (2012)
"Experimental validation of plugging during drop formation in a T-junction"
A. R. Abate, P. Mary, V. van Steijn and D. A. Weitz
Lab Chip 12, 1516 (2012)
"High throughput production of single core double emulsions in a parallelized microfluidic device"
M. B. Romanowsky, A. R. Abate, A. Rotem, C. Holtze, and D. A. Weitz
Lab Chip 12, 802 (2012)
"Non-coalescence of oppositely charged droplets in pH-sensitive emulsions"
T. Liu, S. Seiffert, J. Thiele, A. R. Abate, D. A. Weitz, and W. Richtering
Proc. Natl. Acad. Sci. U.S.A., 109, 384–389 (2011)
"Microfluidic techniques for synthesizing particles"
A. R. Abate, S. Seiffert, A. S. Utada, A. Shum, R. Shah, J. Thiele, W. J. Duncanson, A. Abbaspourad, M. H. Lee, I. Akartuna, D. Lee, A. Rotem, D. A. Weitz
Book Chapter Preprint
"Measuring the elastic modulus of microgels using microdrops"
A.R. Abate, L. Han, L. Jin, Z. Suob, D.A. Weitz
Soft Matter 8, 10032 (2012)
2011
"Efficient encapsulation with plug-triggered drop formation"
A. R. Abate, A. Rotem, J. Thiele, and D. A. Weitz
Phys. Rev. E 84, 031502 (2011)
"Controlling droplet incubation using close-packed plug flow"
P. Mary, A. R. Abate, J. J. Agresti, and D. A. Weitz
Biomicrofluidics 5, 024101 (2011)
"Observation of spatial propagation of amyloid assembly from single nuclei"
T. P. J. Knowles, D. A. White, A. R. Abate, J. J. Agresti, S. I. A. Cohen, R. A. Sperling, E. J. De Genst,C. M. Dobson and D. A. Weitz
Proc. Natl. Acad. Sci. U.S.A., 108, 14746-14751, (2011)
"Early development drug formulation on a chip: Fabrication of nanoparticles using a microfluidic spray dryer"
J. Thiele, M. Windbergs, A. R. Abate, M. Trebbin, H. C. Shum, S. Förster and D. A. Weitz
Lab Chip 11, 2362 (2011)
"On-chip background noise reduction for cell-based assays in droplets"
P. Mary, A. Chen, I. Chen, A. R. Abate, and D. A. Weitz
Lab Chip 11, 2066 (2011)
“Faster multiple emulsification with drop splitting”
A. R. Abate and D. A. Weitz
Lab Chip 11, 1911 (2011)
“Air-bubble-triggered drop formation in microfluidics”
A. R. Abate and D. A. Weitz
Lab Chip 11, 1713 (2011)
“Synthesis of monodisperse microparticles from non-newtonian polymer solutions with microfluidic devices”
A. R. Abate, M. Kutsovsky, S. Seiffert, M. Windbergs, L. F. V. Pinto, A. Rotem, A. S. Utada and D. A. Weitz
Advanced Materials 23, 1757–1760 (2011)
“Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions”
A. R. Abate and D. A. Weitz
Biomicrofluidics, 5, 014107 (2011)
“One-step formation of multiple emulsions in microfluidics”
A. R. Abate, J. Thiele, and D. A. Weitz
Lab Chip, 11, 253-258 (2011)
2010
“High-throughput injection with microfluidics using picoinjectors”
A. R. Abate, T. Hung, P. Mary, J. J. Agresti, and D. A. Weitz
Proc. Natl. Acad. Sci. U.S.A. 107, 19163-19166 (2010)
“Fabrication of polymersomes using double-emulsion templates in glass-coated stamped microfluidic devices”
J. Thiele, A. R. Abate, H. C. Shum, S. Bachtler, S. Forster, and D. A. Weitz
Small, 6, 1723-1727 (2010)
“Patterning microfluidic device wettability using flow confinement”
A. R. Abate, J. Thiele, M. Weinhart, and D. A. Weitz
Lab Chip, 10, 1774-1776 (2010)
“Functional patterning of PDMS microfluidic devices using integrated chemo-masks”
M. B. Romanowsky, M. Heymann, A. R. Abate, A. T. Krummel, S. Fraden, and D. A. Weitz
Lab Chip, 10, 1521-1524 (2010)
“Microfluidic sorting with high-speed single-layer membrane valves”
A. R. Abate, J. J. Agresti, and D. A. Weitz
Appl. Phys. Lett., 96, 203509, (2010)
“Smart microgel capsules from macromolecular precursors”
S. Seiffert, J. Thiele, A. R. Abate, and D. A. Weitz
J. Am. Chem. Soc., 132, 6606-6609 (2010)
“High-throughput fluorescence detection using an integrated zone-plate array”
E. Schonbrun, A. R. Abate, P. Steinvurzel, D. A. Weitz, K. Crozier
Lab Chip, 10, 852-856 (2010)
“Ultrahigh-throughput screening in drop-based microfluidics for directed evolution”
J. J. Agresti, E. Antipov, A. R. Abate, K. Ahn, A. C. Rowat, J. C. Baret, M. Marquez, A. M. Klibanov, A. D. Griffiths, and D. A. Weitz
Proc. Natl. Acad. Sci. U.S.A., 107, 6550 (2010)
“Jamming and growth of dynamical heterogeneities versus depth for granular heap flow”
H. Katsuragi, A. R. Abate, and D. J. Durian
Soft Matter, 6, 3023-3029 (2010)
“Droplet microfluidics for fabrication of non-spherical particles”
H. C. Shum, A. R. Abate, a D. Lee, A. Studart, B. Wang, C. H. Chen, J. Thiele, A. T. Krummel and D. A. Weitz
Macromol. Rapid Comm., 31, 108-118 (2010)
2009
"Functionalized Glass Coating for PDMS Microfluidic Devices"
Abate AR, Lee D, Holtze C, Krummel A, Do T, Weitz DA
Lab-on-a-chip technology: fabrication and microfluidics. Caister Academic Press, Norwich
“Impact of inlet channel geometry on microfluidic drop formation”
Abate AR, Poitzsch A, Hwang Y, Lee J, Czerwinska J, Weitz DA
Phys Rev E Stat Nonlin Soft Matter Phys., 80(2 Pt 2):026310. DOI: 10.1103/PhysRevE.80.026310
“High-order multiple emulsions formed in poly(dimethylsiloxane) microfluidics”
Abate AR, Weitz DA
Small., 5(18):2030-2. doi: 10.1002/smll.200900569
“A multi-color fast-switching microfluidic droplet dye laser”
Tang SK, Li Z, Abate AR, Agresti JJ, Weitz DA, Psaltis D, Whitesides GM
Lab Chip., 9(19):2767-71. DOI: 10.1039/b914066b
“Beating Poisson encapsulation statistics using close-packed ordering”
Abate AR, Chen CH, Agresti JJ, Weitz DA
Lab Chip., 9:2628-2631. DOI: 10.1039/B909386A
“Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices”
Franke T, Abate AR, Weitz DA, Wixforth A
Lab Chip., 9(18):2625-2627. DOI: 10.1039/b906819h
“Microfluidic assembly of magnetic hydrogel particles with uniformly anisotropic structure”
Chen CH, Abate AR, Lee D, Terentjev EM, Weitz DA
Adv. Mater., 21(31):3201-3204. DOI: 10.1002/adma.200900499
“Valve-based flow focusing for drop formation”
Abate AR, Romanowsky MB, Agresti JJ, Weitz DA
Appl. Phys. Lett., 94:023503. DOI: 10.1063/1.3067862
“Janus particles templated from double emulsion droplets generated using microfluidics”
Chen CH, Shah RK, Abate AR, Weitz DA
Langmuir., 25(8):4320-3. DOI: 10.1021/la900240y
2008
“Single-layer membrane valves for elastomeric microfluidic devices”
Abate AR, Weitz DA
Appl. Phys. Lett., 92:243509. DOI: 10.1063/1.2945797
“Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability”
Abate AR, Krummel AT, Lee D, Marquez M, Holtze C, Weitz DA
Lab Chip., 8(12):2157-2160. DOI: 10.1039/b813405g
“Effective temperatures and activated dynamics for a two-dimensional air-driven granular system on two approaches to jamming”
Abate AR, Durian DJ
Phys Rev Lett., 101(24):245701. DOI: 10.1103/PhysRevLett.101.245701
“Glass coating for PDMS microfluidic channels by sol-gel methods”
Abate AR, Lee D, Do T, Holtze C, Weitz DA
Lab Chip., 8(4):516-518. DOI: 10.1039/B800001H
2007
“Topological persistence and dynamical heterogeneities near jamming”
Abate AR, Durian DJ
Phys Rev E Stat Nonlin Soft Matter Phys., 76(2 Pt 1):021306. DOI: 10.1103/PhysRevE.76.021306
“Measurement of growing dynamical length scales and prediction of the jamming transition in a granular material”
Keys AS, Abate AR, Glotzer SC, Durian DJ
Nat. Phys., 3:260-264. DOI: 10.1038/nphys572
“Spatially heterogeneous dynamics in a granular system near jamming”
Abate AR, Durian DJ
Chaos, 17(4):041107. DOI: 10.1063/1.2786011.
“Avalanche statistics and time-resolved grain dynamics for a driven heap”
Abate AR, Katsuragi H, Durian DJ
Phys Rev E Stat Nonlin Soft Matter Phys., 76(6 Pt 1):061301. DOI: 10.1103/PhysRevE.76.061301
2006
“Approach to jamming in an air-fluidized granular bed”
Abate AR, Durian DJ
Phys Rev E Stat Nonlin Soft Matter Phys., 74(3 Pt 1):031308. DOI: 10.1103/PhysRevE.74.031308
2005
“Partition of energy for air-fluidized grains”
Abate AR, Durian DJ
Phys Rev E Stat Nonlin Soft Matter Phys., 72(3 Pt 1):031305. DOI: 10.1103/PhysRevE.72.031305
“Statistical characterization of the forces on spheres in an upflow of air”
Ojha RP, Abate AR, Durian DJ
Phys Rev E Stat Nonlin Soft Matter Phys., 71(1 Pt 2):016313. DOI: 10.1103/PhysRevE.71.016313
“Penetration depth for shallow impact cratering”
Ambroso MA, Santore CR, Abate AR, Durian DJ.
Phys Rev E Stat Nonlin Soft Matter Phys., 71(5 Pt 1):051305. DOI: 10.1103/PhysRevE.71.051305
2002
“Superconductivity, incoherence and Anderson localization in the crystalline organic conductor (BEDT-TTF)3Cl2• 2H2O at high pressures”
Goddard P, Tozer SW, Singleton J, Ardavan A, Abate AR, Kurmoo M
J. Phys. Condens. Matter, 14:7345. DOI: 10.1088/0953-8984/14/31/306
“Adhesives for highly polished surfaces and low temperature: A simple test and results”
Silvera IF, Abate AR, Chijioke A, Pashin A
Rev. Sci. Instrum., 73:2108. DOI: 10.1063/1.1470237